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Pramod Pullarkat
Associate Professor II
Office Phone: +91 9480836220
Email : pramod
Webpage : www.rri.res.in/~pramod/
   
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The interface between biology and physics is getting increasingly blurred.  The main reasons for this are the development of new quantitative techniques to study biological systems and a migration of physicists, mainly from areas like soft matter and statistical physics, to biology.  As a result more and more complex biological phenomena are coming within reach of a physical description. The dynamics of the cytoskeleton is one such problem. Our goal is to improve our understanding of the mechanical and dynamical properties of this complex network of biopolymer filaments, which can interact with molecular motor proteins to generate a very rich variety of "active" phenomena. These include morphological changes, instabilities, and active mechanics. Please see the webpage linked above for more details.
 
 
 
 
   
 
   
 
 
Selected publications
 
1 Dynamics of Membrane Tethers Reveal Novel Aspects of Cytoskeleton-Membrane Interactions in Axons
Anagha Datar, Thomas Bornschlogl, Patricia Bassereau, Jacques Prost, and Pramod A.Pullarkat,
Biophysical Journal, Volume 108, Issue 3, p489-497,2015 (2015)
   
2 Role of actin filaments in correlating nuclear shape and cell spreading
Renu V, Swetavalli Raghavan, Chandrashekar K, Abhijit Majumder, Jyotsna Dhawan, Pramod A. Pullarkat
Plos One, vol. 9, issue 9, e107895, Sep. 2014
   
3 Optical fiber-based force transducer for microscale samples 
Seshagiri Rao R V, Chirag Kalelkar, and Pramod A. Pullarkat 
Review of Scientific Instruments, vol. 84, page 105107, year 2013;
doi: 10.1063/1.4824198
   
4 Drag force as a tool to test active mechanical response of PC12 neurites;
Roberto Bernal, Francisco Melo and Pramod Pullarkat,
Biophysical Journal, vol 98, pp. 515 (2010).
   
5 Shear rheology of a cell monolayer;
Pablo A. Fernandez, Lutz Heymann, Albrecht Ott, Nuri Aksel, Pramod A. Pullarkat,
New Journal of Physics, Vol 9, page 419 (2007).
   
6 Shape oscillations of non-adhering fibroblast cells;
G. Salbreux, J. F. Joanny, J. Prost and P. Pullarkat,
Physical Biology, Vol 4, page 268 (2007).
   
7 Mechanical properties of axons;
Roberto Bernal, Pramod A. Pullarkat and Francisco Melo,
Phys. Rev. Lett. 99 (2007) page 018301.
   
8 Osmotically Driven Shape Transformations in Axons;
(axonal beading or pearling instability ) 
Pramod A. Pullarkat, Paul Dommersnes, Pablo Fernandez,   Jean-Francois Joanny and Albrecht Ott,
Phys. Rev. Lett. 96 (2006) 048104.
   
9 A master relation defines the nonlinear viscoelasticity of single fibroblasts;
Pablo Fernandez, Pramod A. Pullarkat and Albrecht Ott, 
Biophysical Journal. 90 (2006) 3796.
   
   
   
   
   
 
 
   
 
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